PHYTOCHEMICAL AND ANTIOXIDANT PROPERTIES OF VARIOUS EXTRACTS OF MICHELIA CHAMPACA LEAVES
By: Ruwali, Pushpa
.
Contributor(s): Adhikari, Mamta.
Publisher: M P Innovare Academic Sciences Pvt Ltd 2019Edition: Vol.11(5).Description: 56-61p.Subject(s): PHARMACEUTICSOnline resources: Click here
In:
International journal of pharmacy and pharmaceutical scienceSummary: Objective
:
To investigate and compare the phytochemical
s, antioxidant activities of
various
crude extracts from fresh leaves of locally available
plant
Michelia
champaca
belonging to family Magnoliaceae.
Method
s:
The
present study was designed to perform preliminary phytochemical (qualitative and quantit
ative
) analysis of various extracts. The crude
extracts from the leaves
of
M. champaca
were prepared using various
organic
solvents
viz
.
Methanol (MCMET), Ethanol (MCETH), Hexane (MCHEX), and
Chloroform (MCCHLO). In addition, total phenolic (TPC) and total
flavonoid (TFC) contents of various extracts were also measured along with the
evaluation of the antioxidant capacities using most widel
y accepted
in vitro
chemical tests such as DPPH and ABTS radical scavenging assay.
Result
s:
The
methanolic extract
of
M. champaca
showed the presence of maximum phytochemicals (12) when compared to other solvent extracts
viz.
Hexane (10), Ethanol (8) and
Chloroform(7). The amount of phenolic and flavonoids present in solvents were in the order of
Methanol
>Hexane
>Ethanol
>Chloroform. The best antioxidant potential was found in the
Methanol extract. The
Methanolic extract exhibited an IC
50
Conclusio
n:
Phytochemical analysis of
M. champaca
(leave
s) various
extracts showed good
amount
s of phenolic and flavonoid contents
and also
exhibited significant antioxidant activity
. A positive linear correlation between the
antioxidant activities and the total phenolic and flavonoid
contents
of the plant extracts was observed.
Study revealed variations in suc
h reported activities due to different organic extracti
on solvents used.
In overall conclusion,
Michelia
champaca
has good potential as a source of natural antioxidant for animal
health and food industry and further
relevant studies on similar lines would be worthwhile.
| Item type | Current location | Call number | Status | Date due | Barcode | Item holds |
|---|---|---|---|---|---|---|
Articles Abstract Database
|
School of Pharmacy Archieval Section | Not for loan | 2020928 |
Objective
:
To investigate and compare the phytochemical
s, antioxidant activities of
various
crude extracts from fresh leaves of locally available
plant
Michelia
champaca
belonging to family Magnoliaceae.
Method
s:
The
present study was designed to perform preliminary phytochemical (qualitative and quantit
ative
) analysis of various extracts. The crude
extracts from the leaves
of
M. champaca
were prepared using various
organic
solvents
viz
.
Methanol (MCMET), Ethanol (MCETH), Hexane (MCHEX), and
Chloroform (MCCHLO). In addition, total phenolic (TPC) and total
flavonoid (TFC) contents of various extracts were also measured along with the
evaluation of the antioxidant capacities using most widel
y accepted
in vitro
chemical tests such as DPPH and ABTS radical scavenging assay.
Result
s:
The
methanolic extract
of
M. champaca
showed the presence of maximum phytochemicals (12) when compared to other solvent extracts
viz.
Hexane (10), Ethanol (8) and
Chloroform(7). The amount of phenolic and flavonoids present in solvents were in the order of
Methanol
>Hexane
>Ethanol
>Chloroform. The best antioxidant potential was found in the
Methanol extract. The
Methanolic extract exhibited an IC
50
Conclusio
n:
Phytochemical analysis of
M. champaca
(leave
s) various
extracts showed good
amount
s of phenolic and flavonoid contents
and also
exhibited significant antioxidant activity
. A positive linear correlation between the
antioxidant activities and the total phenolic and flavonoid
contents
of the plant extracts was observed.
Study revealed variations in suc
h reported activities due to different organic extracti
on solvents used.
In overall conclusion,
Michelia
champaca
has good potential as a source of natural antioxidant for animal
health and food industry and further
relevant studies on similar lines would be worthwhile.
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